ONGOING TRIALS

TARGET-ABC

A randomized, multi-center trial investigating if targeted antibiotic therapy can improve the prognosis in COPD patients infected with Pseudomonas aeruginosa

Aim

The aim of this study is to investigate whether antibiotic intervention with targeted, pseudomonas active agents in COPD patients with PA can reduce the loss of lung function, reduce the frequency of exacerbations and
mortality.

Protocol (Download)

COPERNICOS

COPD: Eosinophil-guided Reduction of Inhaled COrticoSteroids

Aim

The aim of this study is to determine if a time-updated, eosinophil-guided inhaled corticosteroid treatment in patients with severe and very severe COPD can lead to non-inferior treatment responses to standard treatment with combined ICS, LAMA and LABA, and whether the side-effects of ICS can be reduces by this guided administration. Furthermore, whether the use of azithromycin can reduce the time hospitalized with AECOPD (or other cause) in severe COPD patients.

Protocol (Download)

Recruitment status (Image)

CODEX-P

CopD EXacerbation and Pulmonary hypertension Trial

Aim

The aim of this study is to determine the prevalence of “acute reversible pulmonary hypertension in AECOPD” (AECOPD-rPH) in connection with AECOPD admission, and whether the prognosis is negatively affected by this in the patients with AECOPD-rPH. Furthermore, in patients with AECOPD-rPH, whether the prognosis can be improved by drug treatment of this form of pulmonary hypertension.

Protocol (Download)

Protocol (Danish) (Download)

Completed trials

CORTICO-COP

Protocol (Download)

Statistical Analysis Plan – SAP (Download)

ProPAC-COVID

Protocol (Download)

Statistical Analysis Plan – SAP (Download)

Planned Trials

Thrombo-COP

Protocol to be added soon ..

Development Phase

PERRIsCOPE

Protocol (Download)

TOB-STOP-COP

Protocol (Download)

HeliCOPPter-study

Protocol (Download)

Calcio-COP

Protocol to be added soon ..

Collaborative Investigator-Initiated Trials

TICO

ITAC

OTAC

TESICO

 

For information on these studies, please visit CHIP (INSIGHT) or INSIGHT

CASS Substudies

The effects of mild induced hypothermia on coagulopathy in patients with septic shock

Protocol and SAP (download)